GENEMATES: AN R PACKAGE FOR DETECTING HORIZONTAL GENE CO-TRANSFER BETWEEN BACTERIA USING GENE-GENE ASSOCIATIONS CONTROLLED FOR POPULATION STRUCTURE

GeneMates: an R package for detecting horizontal gene co-transfer between bacteria using gene-gene associations controlled for population structure

Abstract Background Horizontal gene transfer contributes to bacterial evolution through mobilising genes across various taxonomical boundaries.It is frequently mediated by mobile genetic elements (MGEs), which may capture, maintain, and rearrange mobile genes and co-mobilise them between bacteria, causing horizontal gene co-transfer (HGcoT).This ph

read more


A copper switch for inducing CRISPR/Cas9-based transcriptional activation tightly regulates gene expression in Nicotiana benthamiana

Abstract Background CRISPR-based programmable transcriptional activators (PTAs) are used in plants for rewiring gene networks.Better tuning of their activity in a time and dose-dependent manner should allow precise control of gene expression.Here, we report the optimization of a Copper Inducible system called CI-switch for conditional gene activati

read more

Rare sponges from marine caves: discovery of Neophrissospongia nana nov. sp. (Demospongiae, Corallistidae) from Sardinia with an annotated checklist of Mediterranean lithistids

A new record of lithistid demosponges is reported from a western Sardinian karstic cave.The new specimen matches the trait of the genus Neophrissospongia (Corallistidae) for an ectosomal skeleton of radial dichotriaenes, a choanosomal skeleton as a network of dicranoclone desmas, and streptaster/amphiaster microscleres with short spiny rays bearing

read more